Download PDF
Synthesis 1991; 1991(5): 355-356
DOI: 10.1055/s-1991-26464
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

An Improved Synthesis of 2H-1,2,6-Thiadiazine 1,1-Dioxides by Condensation of β-Amino and β-Chloro α,β-Unsaturated Ketones with Sulfamides

Angel Alberola* , José M. Andrés, Alfonso González, Rafael Pedrosa, Martina Vicente
  • *Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Valladolid, Dr. Mergelina s/n, E-47011-Valladolid, Spain
Further Information

Publication History

Publication Date:
29 April 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Symmetrically substituted β-amino α, β-unsaturated ketones react with sulfamide giving 2H-1,2,6-thiadiazine 1,1-dioxides in excellent yields. Unsymmetrically substituted β-amino and β-chloro α, β-unsaturated ketones also react with benzylsulfamide to yield thiadiazine derivatives in good chemical yields and excellent regioselectivity.