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Synthesis 1991; 1991(9): 697-698
DOI: 10.1055/s-1991-26548
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Study of the Reaction Between Cyanohydrins and Chlorosulfonyl Isocyanate. A New, Efficient Method for the One-Pot Synthesis of 2,4-Oxazolidinediones

M. Victoria García* , J. Carlos Menéndez, Mercedes Villacampa, Mónica M. Söllhuber
  • *Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Universidad Complutense, E-28040 Madrid, Spain
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Publication Date:
29 April 2002 (online)

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The reaction between cyanohydrins and chlorosulfonyl isocyanate, followed by acid hydrolysis, provides and efficient route for the one-pot preparation of 5,5-disubstituted 2,4-oxazolidinediones.