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Synthesis 1991; 1991(9): 717-718
DOI: 10.1055/s-1991-26554
DOI: 10.1055/s-1991-26554
paper
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The Mannich Reaction Between Aromatic Ketones, Aromatic Aldehydes and Aromatic Amines
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Publication History
Publication Date:
29 April 2002 (online)
The acid-catalyzed Mannich reaction of acetophenones with benzaldehyde derivatives and aromatic amines gives 1,3-diaryl-3-(arylamino)propanones in high yield.