Synthesis 1991; 1991(11): 939-941
DOI: 10.1055/s-1991-26612
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Enantioselective Synthesis of 2,3-Diamino Acids by the Bislactim Ether Method

Wolfgang Hartwig* , Joachim Mittendorf
  • *Bayer AG, Chemisch Wissenschaftliches Labor Pharma, Postfach 101709, D-5600 Wuppertal 1, Germany
Further Information

Publication History

Publication Date:
29 April 2002 (online)

A method is described for the asymmetric synthesis of both enantiomers of 2-alkyl-substituted 2,3-diaminopropionic acids with different protecting groups using the Schöllkopf-Hartwig bislactim ether method, starting from 2-alkyl-2, 5-dihydro-5-isopropyl-3,6-dimethoxypyrazines.