Download PDF
Synthesis 1991; 1991(11): 965-966
DOI: 10.1055/s-1991-26618
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Ein einfacher Zugang zu 4-Brom-2-(tert-butyldimethylsiloxy)furan aus Tetrahydro-2,4-dioxofuran

Gerhard Jas*
  • *Institut für Organische Chemie der Technischen Universität Berlin, Straße des 17. Juni 115, D-1000 Berlin 12, Germany
Further Information

Publication History

Publication Date:
29 April 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

A Simple Resolution of 4-Bromo-2-(tert-butyldimethylsiloxy)furan from Tetrahydro-2,4-dioxofuran A convenient procedure for the synthesis of 4-bromo-2,5-dihydro-2-oxofuran (4) from tetrahydro-2,4-dioxofuran (3) by reaction with a Vilsmeier reagent prepared from oxalyl bromide and dimethylformamide is given. Compound 3 reacts with tert-butyldimethylsilyl trifluoromethanesulfonate to 4-bromo-2-(tert-butyldimethylsiloxy)furan (5c), a stable synthetic precursor for 2,5-dihydro-2-oxofuranide (1).