Download PDF
Synthesis 1991; 1991(11): 982-984
DOI: 10.1055/s-1991-26623
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Convenient Synthetic Methodology for the Elaboration of the Pyrido[2,3-b]-or [3,4-b]-pyrazine and [1,4]diazepine Skeletons

Axel Couture* , Pierre Grandclaudon
  • *Laboratoire de Chimie Organique Physique, URA CNRS No 351, Université des Sciences et Techniques de Lille Flandres-Artois, F-59655 Villeneuve d'Ascq Cédex, France
Further Information

Publication History

Publication Date:
29 April 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

The condensation of the anion of 3-(formylamino)-2-chloropyridines, 3-(acetylamino)-2-chloro-, -4-chloro- or -2,4-dichloropyridines with various chloro-N,N-dimethylalkylamines gives rise efficiently to 1,2,3, 4-tetrahydropyrido[2,3-b]- or [3,4-b]- pyrazines and to 2,3,4, 5-tetrahydro-1H-pyrido[2,3-b]- or [3,4-b]-[1,4]diazepines.