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Synlett 1992; 1992(1): 33-34
DOI: 10.1055/s-1992-21255
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The Stereocontrolled Synthesis of (2S,3R)-3-Alkyl-L-aspartic Acids Using a 2-Azetidinone Framework as a Chiral Template

Stephen Hanessian* , Kenzo Sumi, Benoit Vanasse
  • *Department of Chemistry, Université de Montréal, C.P. 6128, Succ. A, Montréal, Québec, H3C 3J7, Canada
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Publication Date:
18 September 2002 (online)

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Stereocontrolled processes are described for the synthesis of 3-alkyl-4-carboxy-2-azetidinones and of 3-alkyl-L-aspartic acids of high enantiomeric purity starting from (S)-1-tert-butyldimethylsilyl-4-carboxy-2-azetidinone.