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Synlett 1992; 1992(8): 657-658
DOI: 10.1055/s-1992-21447
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A New and Convenient Synthesis of S-Trifluoromethyl-Containing Amino Acids

Vadim Soloshonok* , Valery Kukhar, Yury Pustovit, Valery Nazaretian
  • *Institute of Bioorganic and Petrol Chemistry of Ukrainian Academy of Sciences, 253160, Kiev, Kharkovskoe Shausse, 50, Ukraine
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Publication Date:
08 March 2002 (online)

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A new method of preparation of enantiomerically pure S-trifluoromethyl-containing amino acids (3 examples) by direct trifluoromethylation of corresponding unprotected amino acids using trifluoromethyl iodide in liquid ammonia under ultraviolet irradiation has been developed.