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Synthesis 1992; 1992(3): 277-278
DOI: 10.1055/s-1992-26089
DOI: 10.1055/s-1992-26089
short paper
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Triethylamine/Aluminum Chloride Promoted Aminolysis of Lactones: A Useful Method for the Preparation of ω-Hydroxyalkanamides
Further Information
Publication History
Publication Date:
17 September 2002 (online)
Primary and secondary aliphatic or aromatic amines react cleanly with medium-ring lactones in the presence of triethylamine/aluminum chloride to afford ω-hydroxyalkanamides in high yield.