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Synthesis 1992; 1992(1/2): 63-68
DOI: 10.1055/s-1992-34177
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Synthesis of New Macrocyclic Amino-Phosphinic Acid Complexing Agents and Their C-and P-Functionalised Derivatives for Protein Linkage

Christopher J. Broan* , Eleanor Cole, Karl J. Jankowski, David Parker, Kanthi Pulukkody, Byron A. Boyce, Nigel R. A. Beeley, Kenneth Millar, Andrew T. Millican
  • *Department of Chemistry, University of Durham, South Road, Durham, DH1 3LE, England
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Publication Date:
18 September 2002 (online)

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The synthesis of various macrocyclic complexing agents with alkyl-and arylphosphinic substituents is reported together with their C-and N-functionalised analogues as active esters suitable for anti-body conjugation.