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Synlett 1993; 1993(12): 929-930
DOI: 10.1055/s-1993-22656
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In Situ Oxazaborolidines, Practical Enantioselective Hydride Reagents

George J. Quallich* , Teresa M. Woodall
  • *Process Research and Development, Central Research Division, Pfizer Inc., Groton, CT 06340
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Publication History

Publication Date:
19 March 2002 (online)

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Oxazaborolidines derived in situ, from erythro 2-amino-1,2-diphenylethanol, norephedrine, or diphenylprolinol and borane, were demonstrated to be practical reagents for enantioselective reduction of prochiral ketones.