PDF herunterladen
Synthesis 1993; 1993(4): 377-379
DOI: 10.1055/s-1993-25867
short paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

An Efficient Stereocontrolled Synthesis of Methyl (9Z,11E,13S)-13-Hydroxyoctadeca-9,11-dienoate (Methyl Coriolate)

Denis Chemin* , Gérard Linstrumelle
  • *Ecole Normale Supérieure, Laboratoire de Chimie, 24 Rue Lhomond F-75231 Paris Cedex 05, France
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
17. September 2002 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

An efficient synthesis of methyl (13S)-coriolate ( S )- 1b is accomplished by the palladium-catalyzed coupling of (1E,3S)-1-iodooct-1-en-3-ol [( S )-3] with methyl dec-9-ynoate (4) followed by selective reduction of the enyne ( S )- 2.