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Synthesis 1993; 1993(9): 855-857
DOI: 10.1055/s-1993-25954
DOI: 10.1055/s-1993-25954
short paper
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Lipase Catalyzed Enantioselective Hydrolysis of (±)-2-Acetoxy-1-chloro-3-phthalimidopropane
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Publication Date:
29 April 2002 (online)
Enzymatic kinetic resolution of (±)-2-acetoxy-1-chloro-3-phthalimidopropane (6) was achieved with Pseudomonas sp. lipase, affording (-)-5 with nearly complete enantioselectivity (ee's 95-99%).