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Synlett 1994; 1994(5): 319-324
DOI: 10.1055/s-1994-22840
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Molecular Recognition of Modified Porphyrins

Yasuhisa Kuroda* , Hisanobu Ogoshi
  • *Department of Synthetic Chemistry and Biological Chemistry Kyoto University, Kyoto 606-01, JAPAN
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Publication Date:
22 March 2002 (online)

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Functionalized porphyrins are very useful for mimicking biochemical functions of heme enzymes. The flat and relatively rigid structure of porphyrins make it easy to design and construct various types of molecular recognition sites on a porphyrin plane. Porphyrins are also very attractive molecules as a "platform" for molecular recognition from the synthetic chemistry viewpoint. In this article, the methodology for syntheses of recognition sites on porphyrins and resulting functions are described. 1. Introduction 2. Molecular Recognition of Nucleobase 3. Molecular Recognition of Amino Acid 4. Molecular Recognition of Hydrophobic Molecule 5. Conclusion