Synlett 1994; 1994(5): 325-329
DOI: 10.1055/s-1994-22841
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Synthetic Studies towards Phorbols: Synthesis of B or C Ring Substituted Phorbol Skeletons in the Naturally Occurring Form

Kazuyuki Sugita* , Kazuhiko Shigeno, Charles F. Neville, Hiroaki Sasai, Masakatsu Shibasaki
  • *Faculty of Pharmaceutical Sciences, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113, Japan
Further Information

Publication History

Publication Date:
22 March 2002 (online)

The optically active phorbol skeletons with an allylic alcohol moiety in B ring 2 or a hydroxyl group in C ring 3 have been constructed in a stereocontrolled manner starting with (+)-3-carene.