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Synthesis 1994; 1994(1): 43-46
DOI: 10.1055/s-1994-25402
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Synthesis of 2-Amino-6-phenyl-4H-pyran-4-ones

Joel Morris* , Donn G. Wishka
  • *Medicinal Chemistry Research, Upjohn Laboratories, The Upjohn Company, Kalamazoo, Michigan 49001, USA
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Publication Date:
17 September 2002 (online)

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The treatment of a series of phenylacetylenic ß-keto amides with methanesulfonic acid produces a high yielding intramolecular cyclization to the corresponding 2-amino-6-phenyl-4H-pyran-4-ones.

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