Download PDF
Synthesis 1994; 1994(4): 427-431
DOI: 10.1055/s-1994-25491
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of α,α-Dialkoxy Imines and α-Keto Acetals

Norbert De Kimpe* , Elena Stanoeva, Marc Boeykens
  • *Department of Organic Chemistry, Faculty of Agricultural and Applied Biological Sciences, University of Gent, Coupure Links 653, B-9000 Gent, Belgium
Further Information

Publication History

Publication Date:
17 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

A convenient synthesis of monoacetals of α-diones, i. e. α-keto acetals, was developed by silver ion induced alcoholysis of regiospecifically formed α-bromo-α-chloro ketones. Similarly, the corresponding α,α-dialkoxy ketimines were synthesized from silver ion induced alcoholysis of α-bromo-α -chloro ketimines. Both methods provide an easy access to protected forms of α-diones, useful as building blocks in organic chemistry.