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Synthesis 1994; 1994(8): 789-791
DOI: 10.1055/s-1994-25575
short paper
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A Facile Procedure for the Reduction of Azido Nucleosides to Amines Using Polymer Bound Triphenylphosphine

Torsten Holletz* , Dieter Cech
  • *Fachbereich Chemie der Humboldt-Universität zu Berlin, Institut für Organische und Bioorganische Chemie, Hessische Str. 1-2, D-10099 Berlin, Germany
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Publication Date:
17 September 2002 (online)

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A very convenient reduction of azido nucleosides to amines under mild conditions using polystyryl diphenylphosphine resin is described. The method requiers only a filtration and evaporation process for product isolation.