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Synthesis 1994; 1994(10): 1023-1025
DOI: 10.1055/s-1994-25628
short paper
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A Facile Procedure for the Synthesis of N-Formyl Amino Acid Esters

T. Chancellor* , Charles Morton
  • *Vitamins Research and Development, Hoffmann-La Roche, Nutley, New Jersey 07110, USA
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Publikationsdatum:
27. September 2002 (online)

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A variety of amino acid ester hydrochlorides react with triethyl orthoformate (TEOF) or trimethyl orthoformate (TMOF) to give the N-formyl amino acid ester in good yield and high optical purity.