PDF herunterladen
Synthesis 1994; 1994(12): 1310-1312
DOI: 10.1055/s-1994-25686
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of a 4′-Selenated 2-Deoxyadenosine Derivative: A Novel Precursor suitable for the Preparation of Modified Oligonucleotides

Bernd Giese* , Peter Erdmann, Thomas Schäfer, Urs Schwitter
  • *Department of Chemistry, University of Basel, St. Johanns Ring 19, CH-4056 Basel, Switzerland
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
25. April 2002 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

Swern oxidation, subsequent selenation and reduction gave the selenated deoxyadenosine derivatives 4a and 4b. Isomer 4b as converted into the phosphoramidite 7, a building block for modified oligonucleotides 8.