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Synthesis 1995; 1995(2): 136-138
DOI: 10.1055/s-1995-3876
DOI: 10.1055/s-1995-3876
short paper
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Stereospecific Tandem Michael Addition-Aldol Condensation-Lactonization Reactions: A Route to Spirocyclopentenolactone
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Publikationsverlauf
Publikationsdatum:
31. Dezember 2000 (online)
Spirocyclopentenolactone 7 was prepared in one pot from α-methylenecyclopentenone (1) via a tandem Michael addition-aldol condensation-lactonization reaction.
Michael initiated ring closure (MIRC) - spirocyclopentenolactone - stereospecific tandem Michael addition-aldol condensation-lactonization reactions