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Synthesis 1995; 1995(8): 917-919
DOI: 10.1055/s-1995-4031
short paper
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A Generalized and Efficient Synthesis of 3-Amino-, 3-(N-Alkylamino)-, 3-(N,N-Dialkylamino)-5-alkyl-1,2,4-oxadiazoles by Irradiation of 3-Alkanoylamino-4-phenyl-1,2,5-oxadiazoles (Furazans)

Silvestre Buscemi, Nicolò Vivona* , Tullio Caronna
  • *Dipartimento di Chimica Organica, Università di Palermo, Via Archirafi 20, I-90123, Palermo, Italy
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Publication Date:
31 December 2000 (online)

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Irradiation of 3-alkanoylamino-4-phenyl-1,2,5-oxadiazoles (furazans) at λ=310 nm in methanol and in the presence of ammonia, primary or secondary aliphatic amines produced excellent yields of 3-amino-, 3-(N-alkylamino)-, 3-(N,N-dialkylamino)-5-alkyl-1,2,4-oxadiazoles.

3-alkanoylaminofurazans photochemical behaviour synthesis of 3-amino-(or 3-N-substituted amino)-5-alkyl-1,2,4-oxadiazoles