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Synthesis 1995; 1995(9): 1053-1065
DOI: 10.1055/s-1995-4074
review
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Reduction of Nitro-Substituted Tertiary Alkanes

Claus D. Weis, George R. Newkome*
  • *Center for Molecular Design and Recognition, Department of Chemistry, University of South Florida, Tampa, Florida 33620 USA, Fax +1(813)9744962; E-mail GNEWKOME@RESEARCH.USF.EDU
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Publication History

Publication Date:
31 December 2000 (online)

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In the course of preparing a series of convenient building blocks for the construction of cascade macromolecules, the need for facile, high yield procedures for amino-tert-alkanes from the corresponding nitroalkanes was apparent. This review summarizes the reduction of nitro-substituted tertiary alkanes.

reductions of nitro moieties - catalytic reduction - branched aliphatic primary amines - dendritic building blocks