Download PDF
Synlett 1995; 1995(1): 51-52
DOI: 10.1055/s-1995-4877
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

α-Alkenylation of Ketones with 1-Alkynes

Akio Hayashi, Masahiko Yamaguchi* , Masahiro Hirama
  • *Department of Chemistry, Faculty of Science, Tohoku University, Aoba, Sendai 980-77, Japan
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

SnCl4-Bu3N reagent promotes α-alkylidenation of ketones with 1-alkynes giving (E)- α-enones. When TMSCl is added to this mixture, α-alkenylation takes place giving β-enones.

γ-stannyl-α-enone - TMSCl - α-enone - β-enone - regioselective protonation