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Synlett 1995; 1995(11): 1151-1152
DOI: 10.1055/s-1995-5211
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Synthesis of Ailanthoidol, a Benzofuran Natural Product

R. W. Bates* , T. Rama-Devi
  • *Department of Chemistry, University of North Texas, Denton, TX 76205, USA
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Publication Date:
31 December 2000 (online)

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A simple synthesis of ailanthoidol has been achieved using palladium/copper catalyzed reactions for key steps. The final step is a simultaneous deprotection and cyclization in a basic medium.

Benzofuran - palladium catalysis - o-alkynylphenol - Castro-Stephens reaction