Synthesis 1996; 1996(9): 1082-1084
DOI: 10.1055/s-1996-4338
short paper
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Substituted Methyl 5β-Cholan-24-oates; Part III: Synthesis of a Novel Cholaphane from Ethylene Glycol Diester of Lithocholic Acid by Cyclization with Terephthalic Acid

Erkki Kolehmainen* , Jari Tamminen, Kari Lappalainen, Tuire Torkkel, Raimo Seppälä
  • *Department of Chemistry, University of Jyväskylä, FIN-40351 Jyväskylä, Finland, Fax +358(41)622501; E-mail ekolehmainen@iylk.iyu.fi
Further Information

Publication History

Publication Date:
31 December 2000 (online)

A novel cholaphane, containing both an aliphatic and an aromatic spacer, has been prepared from ethylene glycol diester of 3α-hydroxy-5β-cholan-24-oic acid (lithocholic acid) by cyclization (Yamaguchi method) with terephthalic acid.