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Synthesis 1996; 1996(10): 1223-1226
DOI: 10.1055/s-1996-4358
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Synthesis of Chiral Triamines and Diamines from Amino Acids

George Kokotos* , Theodoros Markidis, Violetta Constantinou-Kokotou
  • *Department of Chemistry, University of Athens, Panepistimiopolis, Athens 15771, Greece, Fax +30(1)7249101
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Publication History

Publication Date:
31 December 2000 (online)

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Selectively protected (2S)-1,2,6-triaminohexane 4 was prepared from L-lysine by reduction of the amino acid, replacement of the hydroxy group by an azido group and selective reduction. Following the same method vicinal diamines 11 and 13 bearing a third functional group were synthesized from L-glutamic acid.

chiral triamines - diamines - amino acids - amino alcohols - selectively protected amines