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Synthesis 1996; 1996(12): 1422-1424
DOI: 10.1055/s-1996-4421
DOI: 10.1055/s-1996-4421
short paper
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Synthesis of the Dipotassium Salts of Methyl α-D-Mannopyranoside 6-Phosphorothioate and D-Mannose 6-Phosphorothioate
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Publication History
Publication Date:
31 December 2000 (online)
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Dipotassium methyl α-D-mannopyranoside 6-phosphorothioate (4) and dipotassium D-mannose 6-phosphorothioate (7) have been prepared from per-O-trimethylsilyl derivatives of methyl α-D-mannopyranoside and D-mannopyranose, respectively, through reaction sequences involving selective cleavage in the pyranoside ether, and selective replacement in the pyranose ether, of a 6-O-trimethylsilyl group.
carbohydrates - mannose - phosphitylation - phosphorothioates - inhibitors