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Synlett 1996; 1996(5): 477-478
DOI: 10.1055/s-1996-5454
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A Stereoselective Route to trans-1-Arylthio-2-aminoindanes

Barry S. Orlek*
  • *SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, Third Avenue, Harlow, Essex CM19 5AW, UK
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Publication History

Publication Date:
31 December 2000 (online)

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The acid catalysed ring opening of the 2-ethoxy oxazoline 1 with aryl thiols provides a convenient route to the trans-1-arylthio-2-aminoindane derivatives 4a-e.

oxazoline - thiol - indane