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Synlett 1996; 1996(7): 695-696
DOI: 10.1055/s-1996-5568
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Synthesis of Substituted Isoxazoles from (Z)-3-Alkyl-3-Nitro-2-Phenylpropenenitriles using Baker’s Yeast

Arturo Navarro-Ocaña* , Manuel Jiménez-Estrada, M. Beatriz González-Paredes, Eduardo Bárzana
  • *Instituto de Química, Facultad de Química. Universidad Nacional Autónoma de México, Cd. Universitaria, D.F. 04510, Coyoacán, México, D.F.
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Publication History

Publication Date:
31 December 2000 (online)

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(Z)-3-Aryl- and (Z)-3-Alkyl-2-phenyl-3-nitropropenenitriles were biohydrogenated with baker’s yeast to 5-Amino-3-aryl- and 5-Amino-3-alkyl-4-phenylisoxazoles in good to moderate yields.

Substituted isoxazoles from (Z)-3-alkyl-3-nitro-2-phenylpropenenitriles using baker’s Yeast