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Synlett 1997; 1997(11): 1261-1262
DOI: 10.1055/s-1997-1031
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One Pot Synthesis of Fluoroalkyl Pyrimidines from α-Fluoroalkyl Carbonyl Compounds, Orthoesters and Ammonium Carbonate

Bing-Hao Luo, Hui-Ping Guan, Chang-Ming Hu*
  • *Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China
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Publication History

Publication Date:
31 December 2000 (online)

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Fluoroalkyl pyrimidines have been synthesized from one pot reaction of α-fluoroalkyl carbonyl compounds, orthoesters and ammonium carbonate. The possible reaction pathway is suggested.

one pot synthesis - fluoroalkyl pyrimidine - fluorine-containing building block