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Synlett 1997; 1997(12): 1345-1348
DOI: 10.1055/s-1997-1055
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Towards a Total Synthesis of Ulapualide A. A Concise Synthesis of the tris-Oxazole Macrolide Core and Entire Carbon Skeleton

Shital K. Chattopadhyay, Gerald Pattenden*
  • *Department of Chemistry, Nottingham University, University Park, Nottingham NG7 2RD, England, Fax 0115 9513535; GP@nottingham.ac.uk
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Publication Date:
31 December 2000 (online)

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A concise synthesis of the tris-oxazole based macrocyclic core viz 14 of ulapualide A 1, incorporating all the correct stereogenic centres at C-3 and along the C25-C40 portion of the natural product, is described.

tris-oxazoles - macrolides - sea-slug metabolites