Download PDF
Synthesis 1997; 1997(11): 1321-1324
DOI: 10.1055/s-1997-1354
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Convenient and Regioselective Synthesis of 4-Trifluoromethylpyridines

Isamu Katsuyama, Seiya Ogawa, Yoshihiro Yamaguchi, Kazumasa Funabiki, Masaki Matsui, Hiroshige Muramatsu, Katsuyoshi Shibata*
  • *Department of Chemistry, Faculty of Engineering, Gifu University, Yanagido, Gifu 501-11, Japan, Fax +81(58)2301893
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Trifluoromethyl-substituted β-diketones regioselectively react with primary enamines such as β-aminocrotononitrile and ethyl β-aminocrotonate, providing moderate to good yields of 4-trifluoro-methylpyridines.

trifluoromethyl - β-diketones - β-aminocrotononitrile - ethyl β-aminocrotonate - 4-trifluorometehylpyridines