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Synlett 1997; 1997(5): 553-554
DOI: 10.1055/s-1997-3205
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Synthesis of α-Trinositol Analogues Derived from D-(-)-Quinic Acid as Affinity Probe Precursors

P. Guédat1 , N. Rehnberg2 , B. Spiess1 , G. Schlewer3
  • 1Laboratoire de Pharmacochimie Moléculaire UPR421 du CNRS Faculté de Pharmacie, 74, route du Rhin, 67401 Illkirch, France
  • 2Perstorp Pharma, Perstorp S-284 80, Sweden
  • 3Laboratoire de Pharmacochimie Moléculaire UPR421 du CNRS Faculté de Pharmacie, 74, route du Rhin, 67401 Illkirch, France, Fax 33 388 67 47 94, e-mail schlewer@pharma.u-strasbg.fr
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Publication History

Publication Date:
31 December 2000 (online)

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D-(-)-Quinic acid was appropriately protected to permit the phosphorylation of the three vicinal hydroxyl groups. Final deprotection lead to tris(phosphates) possessing the same configuration as the parent α-trinositol and an arm suitable for the attachement of a photoactivable group.

α-trinositol - Inositol-phosphate - quinic acid derivatives