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Synlett 1997; 1997(5): 555-556
DOI: 10.1055/s-1997-3208
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One-Pot Synthesis of Dioxazaphosphocanes - Cyclic Phosphotriesters Analogues of Phospholipids

Jean-Michel Grévy, Jacques Bellan* , Lydia Lamandé, Anne Pujo
  • *Synthèse et Physicochimie Organique, ESA. CNRS 5068, Université Paul Sabatier, 118 route de Narbonne, F-31062 Toulouse cedex 4, France, Fax 33 (0)5 61 55 60 11; e-mail: spco@iris.ups-tlse.fr
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Publication History

Publication Date:
31 December 2000 (online)

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The reaction of constrained dioxazaphosphabicyclo[3.3.0]octane with acid chlorides provides a facile and efficient one-pot route to eight membered cyclic phosphoric and thiophosphoric esters.

dioxazaphosphocanes - cyclic phosphotriesters - phospholipase inhibitors