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Synlett 1997; 1997(5): 561-562
DOI: 10.1055/s-1997-3211
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A New and Facile Method for the Preparation of 3-Substituted Pyrazolo[3,4-c]pyridines

Panagiotis Marakos1 , Nicole Pouli2 , Dean S. Wise3 , Leroy B. Townsend4
  • 1Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens, Panepistimiopolis-Zografou 15771, Athens, Greece, Fax +30-1-723-8297; e-mail: pmarakos@atlas.uoa.ariadne-t.gr
  • 2Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens, Panepistimiopolis-Zografou 15771, Athens, Greece, Fax +30-1-723-8297
  • 3Department of Medicinal Chemistry, College of Pharmacy, The University of Michigan, Ann Arbor, Michigan 48109, USA
  • 4Department of Medicinal Chemistry, College of Pharmacy; Department of Chemistry, College of Literature, Science and the Arts, The University of Michigan, Ann Arbor, Michigan 48109, USA
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Publication History

Publication Date:
31 December 2000 (online)

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An efficient and facile method for the synthesis of 3-substituted pyrazolo[3,4-c]pyridines is described starting from the readily accessible 3-acetamido-2-methoxy-4-methylpyridine.

3-alkylpyrazolo[3,4-c]pyridines - 3-arylalkylpyrazolo[3,4-c]pyridines - 3-acetamido-4-alkylpyridine ring closure