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Synlett 1997; 1997(2): 199-201
DOI: 10.1055/s-1997-753
DOI: 10.1055/s-1997-753
letter
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Enantioselective Synthesis of Aurilide, a Cytotoxic 26-Membered Cyclodepsipeptide of Marine Origin
Further Information
Publication History
Publication Date:
31 December 2000 (online)
![](https://www.thieme-connect.de/media/synlett/199702/lookinside/thumbnails/10.1055-s-1997-753-1.jpg)
Aurilide (1), a novel cyclodepsipeptide isolated from the Japanese sea hare Dolabella auricularia, was enantioselectively synthesized, and the present result unambiguously confirmed its stereostructure. In addition, the cytotoxicity of 1 was evaluated by employing synthetic 1.
aurilide - cytotoxic 26-membered cyclodepsipeptide - enantioselective synthesis - anti aldol reaction - macrolactamization