Synlett 1997; 1997(3): 271-272
DOI: 10.1055/s-1997-771
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Desulfonylation of Amides Using Samarium Iodide

Haydn Knowles, Andrew F. Parsons* , Robert M. Pettifer
  • *Department of Chemistry, University of York, Heslington, York, YO1 5DD, UK
Further Information

Publication History

Publication Date:
31 December 2000 (online)

The desulfonylation of N-sulfonyl amides can be achieved in reasonable to excellent yield by reaction with samarium(II) iodide (SmI2) in THF at room temperature. Deprotection of acyclic and cyclic amides bearing aryl and alkylsulfonyl groups is possible.