Download PDF
Synlett 1997; 1997(3): 285-286
DOI: 10.1055/s-1997-773
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A New Modification of the Friedländer Synthesis via ortho-Dilithiated N-Pivaloylanilines

J. Ignacio Ubeda, Mercedes Villacampa, Carmen Avendaño*
  • *Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Universidad Complutense, 28040 Madrid, Spain, Fax 34 1 394 1822
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Formylation of ortho-dilithiated N-pivaloylanilines followed by treatment with carbonyl compounds and KHMDS affords 3- or 2,3-substituted quinoline derivatives in a one-pot reaction.

Friedländer reaction - quinoline derivatives - pivaloylanilines - ortho-lithiation