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Synlett 1997; 1997(3): 275-276
DOI: 10.1055/s-1997-784
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An Enantioselective Synthesis of (-)-α-Kainic Acid via Thiyl Radical Addition-Cyclization-Elimination Reaction

Okiko Miyata, Yoshiki Ozawa, Ichiya Ninomiya, Takeaki Naito*
  • *Kobe Pharmaceutical University, Motoyamakita, Higashinada, Kobe 658, Japan, Fax 078 441 7556; E-mail: taknaito@kobepharma-u.ac.jp
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Publication Date:
31 December 2000 (online)

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An enantioselective synthesis of (-)-α-kainic acid has been achieved via the route involving thiyl addition-cyclization-elimination reaction.

kainoid - kainic acid - radical cyclization - total synthesis - addition-cyclization-elimination