Synlett 1998; 1998(8): 849-850
DOI: 10.1055/s-1998-1799
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Sc(OTf)3, an Efficient Catalyst for Formation and Deprotection of Geminal Diacetates (Acylals); Chemoselective Protection of Aldehydes in Presence of Ketones

Varinder K. Aggarwal* , Silvia Fonquerna, Graham P. Vennall
  • *Department of Chemistry, University of Sheffield, Brook Hill, Sheffield S3 7HF, UK
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Scandium triflate (2 mol%) has been found to be an extremely efficient catalyst for the addition of acetic anhydride to both aromatic and aliphatic aldehydes. Deprotection of the resulting geminal diacetates (acylals) was achieved using the same catalyst in the presence of water.