Synlett 1998; 1998(8): 847-848
DOI: 10.1055/s-1998-1821
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Asymmetric Synthesis XXVIII: Novel Chiral Aminophosphine Phosphinite Ligand and Its Application in Homogenous Catalytic Asymmetric Hydrogenation of Dehydroamino Acid Derivatives

Aiqiao Mi* , Rongliang Lou, Yaozhong Jiang, Jingen Deng, Yong Qin, Fangmin Fu, Zhi Li, Wenhao Hu, Albert S. C. Chan
  • *Union Laboratory of Asymmetric Synthesis, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 61 00 41, China; Fax (00 86) (0 28) 5 22 39 78; E-mail: clf@mail.sc.cninfo.net
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Novel chiral aminophosphine phosphinite, DPAMPP was designed and synthesized from (1S,2R)-1,2-diphenyl-2-aminomethanol. Its cationic rhodium complex has been found to be an excellent catalyst for enantioselective hydrogenation of dehydroamino acids (more than 95.0% e.e.).