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Synthesis 1998; 1998(5): 763-770
DOI: 10.1055/s-1998-4489
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An Improved Dienophile-Induced Access to Enantiopure 2,4-Dideoxysugar Lactones via Hetero Diels-Alder Reaction: Synthesis of the (+)-Lactone Moiety of Compactin

Gilles Dujardin* , Sandrine Rossignol, Eric Brown
  • *Laboratoire de Synthèse Organique (associé au CNRS), Faculté des Sciences, Avenue Olivier Messiaen, F-72085 Cedex 9, Le Mans, France; Fax + 33(2)43 83 33 66; E-mail: dujardin@univ-lemans.fr
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Publication History

Publication Date:
31 December 2000 (online)

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methyl (E)-tert-butoxymethylenepyruvate - chiral enol ethers - (4 + 2) heterocycloaddition - intramolecular Mitsunobu reaction - (+)-compactin lactone