The influence of the oral administration of an aqueous-ethanolic extract
of a mixture of Thujae occidentalis herba, Baptisiae tinctoriae radix, Echinaceae
purpureae radix and Echinaceae pallidae radix, on the immune response in mice
was investigated. The data show that the extract significantly enhances the
antibody response to sheep red blood cells (SRBC), induces an increase in
the numbers of splenic plaque forming cells (PFC) and an increase in the titer
of specific antibodies in the sera of treated animals. The long-term application
of the extract over several months also stimulated the PFC-response without
affecting spleen weight, total cell yield per spleen or white blood cell count
in mice.
Herbal immunomodulator -
Echinacea spp. -
Baptisia tinctoria
-
Thuja occidentalis
- peroral application - long-term application - PFC response in mice
