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Synlett 1999; 1999(6): 825-833
DOI: 10.1055/s-1999-2726
new tools in synthesis
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In Vitro Selected Oligonucleotides as Tools in Organic Chemistry

Andres Jäschke* , Christian Frauendorf, Felix Hausch
  • *Institut für Biochemie der Freien Universität Berlin, Thielallee 63, D-14195 Berlin, Germany; Fax (+49) 30 8 38 50 60; E-mail: jaschke@chemie.fu-berlin.de
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Publication History

Publication Date:
31 December 1999 (online)

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DNA and RNA molecules have been isolated from synthetic combinatorial libraries that are able to bind a variety of small organic molecules and catalyze different chemical reactions. The properties of these molecules as well as the techniques for their identification are discussed with respect to potential applications in organic synthesis.

RNA catalysis - in vitro selection - aptamers - ribozymes - combinatorial chemistry