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Synlett 1999; 1999(6): 753-755
DOI: 10.1055/s-1999-2736
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Trichloroacetimidate as an Efficient Protective Group for Alcohols

Biao Yu* , Hai Yu, Yongzheng Hui, Xiuwen Han
  • *State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China
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Publikationsdatum:
31. Dezember 1999 (online)

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The trichloroacetimidate is disclosed to be a general and efficient protective group for alcohols, which can be deprotected under mild acidic, basic, or neutral conditions, and has orthogonal stability with the acetate and tert-butyldimethylsilyl (TBS) protections.

trichloroacetimidate - protective group - alcohol