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Synlett 1999; 1999(10): 1523-1533
DOI: 10.1055/s-1999-2880
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Venturing into Catalysis Based Natural Product Synthesis

Alois Fürstner*
  • *Max-Planck-Institut für Kohlenforschung, D-45470 Mülheim/Ruhr, Germany; Fax + 49(2 08)3 06 29 80; E-mail: fuerstner@mpi-muelheim.mpg.de
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Publication Date:
31 December 1999 (online)

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Some total syntheses from our laboratory targeting structurally diverse and biologically active pyrrole alkaloids, furanoterpenes, macrolide antibiotics and carbohydrates are summarized. All of them rely on new and/or improved transition metal catalyzed transformations as the key steps, intend to minimize the total number of operations in the overall sequences, and aim at valorizing bulk chemicals.

palladium - platinum - metathesis - Suzuki coupling - mannosides