Download PDF
Synthesis 1999; 1999(1): 55-57
DOI: 10.1055/s-1999-3667
short paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Convenient Trifluoroacetylation Reagent: N-(Trifluoroacetyl)succinimide

Alan R. Katritzky* , Baozhen Yang, Guofang Qiu, Zhongxing Zhang
  • *Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA; Fax +1(352)3 92 91 99; E-mail: Katritzky@chem.ufl.edu
Further Information

Publication History

Publication Date:
31 December 1999 (online)

  PDF Download  Permissions and Reprints All articles of this category

N-(Trifluoracetyl)succinimide, easily prepared from trifluoroacetic anhydride and succinimide forms a novel, convenient trifluoracetylating reagent. It trifluoroacetylates alcohols, phenols and amines, to generate trifluoroacetate esters, and trifluoracetamides in excellent yields with very efficient work up procedures.

N-(trifluoroacetyl)succinimide - trifluoroacetylating reagent - trifluoroacetate esters - trifluoroacetamides