Download PDF
Synthesis 1999; 1999(1): 138-144
DOI: 10.1055/s-1999-3681
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Solid-Phase Synthesis of Functionalized 6-, 7- and 8-Membered Azacycles via Olefin Metathesis

Josef Pernerstorfer* , Matthias Schuster, Siegfried Blechert
  • *Institut für Organische Chemie der Technischen Universität, Straße des 17. Juni 135, D-10623 Berlin, Germany; Fax +49(30)31 42 36 19; E-mail: sibl@wap0105.chem.tu-berlin.de
Further Information

Publication History

Publication Date:
31 December 1999 (online)

  PDF Download  Permissions and Reprints All articles of this category

A modular solid-phase synthesis of functionalized azacycles is described. The approach is based on a ring-closing metathesis to form heterocycles of different ring sizes. Furthermore, the epoxidation of the primarily formed cyclic double bond has been investigated.

metathesis - solid-phase synthesis - nitrogen heterocycles - epoxidation