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Semin Liver Dis 2000; 20(4): 523-532
DOI: 10.1055/s-2000-13160
Copyright © 2000 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Immunosuppression in Liver Transplantation

Mark S. Cattral1 , Leslie B. Lilly2 , Gary A. Levy2
  • 1Department of Surgery and the Multi Organ Transplant Program, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada and
  • 2Department of Medicine, and the Multi Organ Transplant Program, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
Further Information

Publication History

Publication Date:
31 December 2000 (online)

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ABSTRACT

Prevention of graft rejection while minimizing morbidity remains the single most important objective in liver transplantation. Advances in immunosuppression have provided excellent patient and graft survival with relatively low incidences of acute rejection. However, it is apparent that the toxicity of the present immunosuppressive drugs accounts for much of the morbidity after transplantation. Attention is now being focused on combination drug therapies to reduce morbidity while maintaining the excellent results achieved with present immunosuppressive agents.

KEYWORD

liver transplantation - immunosuppression - rejection

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